non-glycosidic pyranocoumarins Pd-Ia, Pd-Ib, Pd-II and Pd- III, and the angular glycosidic pyranocoumarins praeroside II, praeroside III, praeroside IV and praeroside V, along with linear glycosidic furocoumarin praeroside I, from Bai-Hua

The traditional Chinese medicine, Qianhu, which consists of the roots of Peucedanum praeruptorum DUNN. and P. decursivum MAXIM. (Umbelliferae), is used for treatment of respiratory disease and pulmonary hypertension. In the course of our search for the active ingredients of Qianhu, we have reported the structures and biological activities of coumarins isolated from both plants. We isolated the angular non-glycosidic pyranocoumarins Pd-Ia, Pd-Ib, Pd-II and PdIII, and the angular glycosidic pyranocoumarins praeroside II, praeroside III, praeroside IV and praeroside V, along with linear glycosidic furocoumarin praeroside I, from Bai-Hua Qianhu (Peucedanum praeruptorum DUNN.), and the linear non-glycosidic pyranocoumarins Pd-C-I, Pd-C-II, Pd-C-III, Pd-C-IV, Pd-C-V and AD-I, as well as various saponins, from Zi-Hua Qianhu, the root of P. decursivum MAXIM. In addition, we recently isolated two novel angular pyranocoumarin glycosides, peucedanosides A and B, along with apterin and praerosides e and f , from Peucedanum praeruptorum DUNN. In this paper, we report the isolation and structure elucidation of a new simple coumarin glycoside and six known simple coumarins from Bai-Hua Qianhu collected in China.